RWE Modelling

Simulation by Health iQ

Engage with healthcare professionals and payers using bespoke animated models to simulate healthcare pathways.

Simulation models allow you to communicate the impact of introducing a new intervention or a service change by comparing the 'as is' scenario with the proposed change in a risk-free environment.

Health iQ's simulation models are built using a modelling technique called `discrete event simulation' (DES) which codifies the behaviour of a complex real-world system as an ordered sequence of well-defined events. These touchpoints are outlined in a clear pathway which is easy to follow and understand and represents the basis of the model.

The transparent pathway together with the use of real-world data helps to overcome a defensive attitude towards change and can function as a conversation-opener. DES is ideal for simulating health care systems, treatment pathways or health economies as it allows investigation of the real-world impact of a multitude of changes such as medication or device choice, service arrangements, resource use, etc.

The `game based learning' approach allows for greater flexibility than other traditional modelling techniques and is great for communicating a story and conveying a compelling case for change.

Our simulation models incorporate our own unique 2D isometric designs which give them even greater impact.

Health iQ Simulation, brings real world data to life

Demonstrating the value
of your intervention or
service change.

A Simulation model by Health iQ can cover a multitude
of treatment effects and downstream service efficiencies from


New pharmacological treatment delaying time to more complex intervention


Shorter infusion time leading to freeing of capacity


New medical device reducing LOS in hospital leading to freeing of capacity


New drug is better tolerated and avoids a presentation to GP or hospital due to adverse events

Patients reach a stable controlled disease level much quicker which reduces the resource use burden.

Health iQ’s RWE-Powered Global Value Dossier

A Global Value Dossier (GVD) presents a summary of your product value, supported by the most robust and compelling evidence. Traditionally these are primarily based on Systematic Literature Review (SLR), or gathering existing published evidence in the form of previous research and clinical trials. The problem with this approach is that it often doesn’t reflect real-world practice and is out of date in terms of reflecting current treatment pathways.
Unlike many providers of GVDs, Health iQ are specialists in RWE-based research and are able to access longitudinal patient data from across the world.

We house licensed datasets such as HES and CPRD, which provide national coverage of both the primary care and secondary care pathways. We can map out treatment pathways from actual patient data and build cost-effectiveness analysis which incorporates the full cost burden of a condition, including all the co-morbidities and side effects. This allows us to provide RWE-powered dossiers which are more precise, focused and impactful than those relying only on summarising existing research through systematic literature review (SLR).

We access data based on what is most appropriate to support your product's value story. We then conduct new research focused around the key value messages you want to convey, so that the evidence we produce and incorporate into your dossier is built entirely around the need of your product. This creates a far more compelling output than one based on SLR only, which are often general, miss specific data points which do not already exist in the public domain and are not necessarily based on current practice.
As well as delivering quality RWE-supported GVDs, we can also translate the main template into customised local dossiers to suit specific geographies which used to support local engagement with payers, or to inform HTA or formulary submissions.

These will also be supported with data from the local region, again making the dossier relevant, current and focused.

RWE typically included in a Value Dossier (either at Global or Local level):
• Disease epidemiology.
• Burden of illness.
• Treatment pathways.
• Burden of unmet need.
• Summary of supporting clinical research (RCT, PASS etc.)
• Humanistic QOL data.
• Economic studies (Cost-effectiveness analysis, budget impact modelling).

Health iQ's RWE-Powered Cost Effectiveness Analysis

Capture the full picture using comprehensive RWE of the full patient pathway.

Cost effectiveness analysis (CEA) models allow you to represent the costs and effectiveness of an intervention based on the best available evidence. Health iQ’s RWE approach ensures that only the most current, relevant and comprehensive data is used, hence ensuring that our models do not under represent the cost burden of existing treatment pathways, and therefore ensuring that the benefits of your intervention are fairly and correctly presented.

Our models are built in accordance with best practice guidelines and can be delivered either via standard Excel or in a format suited to your device of preference. We construct models to suit all geographies and HTA authorities.

Health iQ's RWE-Powered Budget Impact Modelling

Take budget impact modelling to the next level with RWE.

In a data-savvy market it is vital that your model contains the most up-to-date and robust data. Too often we find that models may look nice on the outside, but their beauty is only skin-deep as they are built from data which is old, imprecise or just unsuitable.

Health iQ are specialists in RWE-based research and can access current longitudinal patient data from sources across the world. We house licensed datasets such as HES and CPRD and are able to construct budget impact models based on real-life pathways and with a true representation of the full cost of care.

Our models all adhere to our core principles of clarity, transparency and robustness of data, whilst still being visually appealing and fully adhering to international standards and best practice.

And if an old-fashioned Excel output is not for you (though we can happily do that too!), we can deliver your model via web or mobile app, whatever best suits you.